Fixable Primary and Large Secondary Osteochondral Defects of the Talus: Evidence-Based Therapy

PROJECT PARTNERS

  • None

FUNDING

  • Department of Orthopedic Surgery, Amsterdam UMC

  • Foundation Friends of ACES

BACKGROUND

An osteochondral lesion in the ankle can occur after a trauma such as an ankle sprain or an ankle fracture. It seems that there are different types of defects from a morphological perspective when considering the defect on the CT scan or intra-operatively. Large fixable lesions can be treated with a fixation techniques, while non-fixable large lesions probably need to undergo some form of osteo(chondral) transplantation. From the present existing research it is evident that there is a scarcity of evidence on the personalized efficacy of these treatment options in an evidence-based manner.

OBJECTIVES

The objective of this thesis is therefore to work towards an evidence-based therapy for patients with osteochondral lesions of the ankle through determining the efficacy of fixation and osteochondral transplantation in an evidence-based manner so it will become evident which therapy works for which individual patient.